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Nano Zinc Oxide Toxicity Varies With Age and Sex in Panagrellus redivivus Environ. Toxicol. (IF 4.4) Pub Date : 2025-05-30
Lola Virág Kiss, Dóra Klára Baranyi, András Ittzés, Anikó Seres, Péter István NagyZnO NPs can adsorb onto soil particles and potentially enter groundwater. Nematodes and other soil microfauna are vital to the soil's health and nutrient cycles, yet they are seriously endangered by ZnO NPs. A dose–response study using Panagrellus redivivus was applied. The study evaluated the effects of ZnO NPs with sizes of 15 and 140 nm on various age groups (J2, J3‐J4 and adult) and sexes. After
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Maternal Exposure to an Environmentally Relevant Phthalate Mixture Modulates the Steroidogenic Genes in the Adrenal Glands Throughout Postnatal Development of Male Rats Environ. Toxicol. (IF 4.4) Pub Date : 2025-05-28
Natália Magosso, Patrick Vieira de Souza, Ariana Musa Aquino, Vanessa Aguiar Rocha, Matheus Naia Fioretto, Luiz Guilherme Alonso Costa, Silvana Gisele Pegorin de Campos, Luiz Fernando Barbisan, Luis Antonio Justulin, Jodi A. Flaws, Wellerson Rodrigo ScaranoPhthalates are a group of chemicals used as plasticizers to enhance the malleability and flexibility of various products. The adrenal glands are responsible for producing hormones that maintain homeostasis, regulate blood pressure, and mediate stress responses. Early exposure of the adrenal glands to environmental toxicants can impair important responses, which can result in damage of adrenal development
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Induction of Netosis by 2,2,4,4‐Tetrabromodiphenyl Ether (BDE‐47) in Cyprinus Carpio Environ. Toxicol. (IF 4.4) Pub Date : 2025-05-27
Zihan Gao, Junchen Yu, Yizhao Huang, Yang Jiang, Jingzeng Cai, Ziwei ZhangPolybrominated diphenyl ethers (PBDEs), extensively utilized as brominated flame retardants, have attained pervasive application in diverse products, thereby manifesting as omnipresent contaminants in the global environmental landscape. Among the PBDEs, 2,2′,4,4′‐Tetrabromodiphenyl ether (BDE‐47) exhibits the broadest distribution and is recognized for its adverse impact on fish. The formation of neutrophil
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Mixture Matters: Exploring the Overlooked Toxicity of Sulfamethoxazole and Trimethoprim in Aquatic Environments Environ. Toxicol. (IF 4.4) Pub Date : 2025-05-23
Bárbara S. Diogo, Sara Rodrigues, Sara C. AntunesSulfamethoxazole (SMX) and trimethoprim (TRIM) are two antibiotics included in the third Watch list to be monitored in inland waters by the Water Framework Directive. However, their mixture (MIX) is overlooked and is especially concerning because it mirrors the real conditions in natural aquatic ecosystems. This study aimed to evaluate the toxic effects of environmentally relevant concentrations of
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RETRACTION: Lipoic Acid and Calligonum Comosumon Attenuate Aroclor 1260‐Induced Testicular Toxicity in Adult Rats Environ. Toxicol. (IF 4.4) Pub Date : 2025-05-22
RETRACTION: H.A.A. Aly, A.M. Alahdal, A.A. Nagy, H.M. Abdallah, E.A. Abdel‐Sattar, and A.S. Azhar, “,” Environmental Toxicology 32, no. (2017): 1147–1157, https://doi.org/10.1002/tox.22310.The above article, published online on 1 September 2016 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the journal Editor‐in‐Chief, April Rodd; and Wiley Periodicals LLC
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Bisphenol A Induces Neuronal Apoptosis and Oxidative Stress Through TRPV4 Channel Signaling Pathways: Protective Role of Alpha‐Lipoic Acid Environ. Toxicol. (IF 4.4) Pub Date : 2025-05-21
Ramazan Çinar, Mustafa NazıroğluBisphenol A (BPA), an environmental toxin, exerts adverse effects by increasing mitochondrial (mROS) and intracellular (iROS) reactive oxygen species, apoptosis, and Ca2+ influx in neurological diseases. However, antioxidants can mitigate these detrimental effects. This study aimed to investigate the protective role of antioxidant alpha‐lipoic acid (ALA) against BPA‐induced TRPV4 channel stimulation
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MiR‐1 Is Regulated by Hydrogen Peroxide via MAPK and Limits Cell Migration and Invasion Environ. Toxicol. (IF 4.4) Pub Date : 2025-05-16
Maricica Pacurari, Irmanecia Cox, Ibrahim FarahMicroRNA‐1 (miR‐1) is a conserved microRNA that is highly expressed in skeletal and cardiac muscle tissues. Moreover, miR‐1 regulates genes and has critical roles in cell migration and invasion. Downregulation of miR‐1 has been found in many pathologies of numerous organs, including the lungs. What exactly contributes to the downregulation of miR‐1 is not fully understood, and in the present study
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RETRACTION: Identification of Potential Therapeutic Targets for Breast Cancer Using Mendelian Randomization Analysis and Drug Target Prediction Environ. Toxicol. (IF 4.4) Pub Date : 2025-05-13
RETRACTION: Z. Huang, H. Zheng, H. Wang, H. Ning, A. Che, and C. Cai, “,” Environmental Toxicology (EarlyView): https://doi.org/10.1002/tox.24249.The above article, published online on 6 April 2024 in Wiley Online Library (http://onlinelibrary.wiley.com/), has been retracted by agreement between the journal Editor‐in‐Chief, April Rodd; and Wiley Periodicals LLC. Following an investigation by the publisher
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RETRACTION: Single‐Cell Transcriptome Sequencing Analysis Reveals Intra‐Tumor Heterogeneity in Esophageal Squamous Cell Carcinoma Environ. Toxicol. (IF 4.4) Pub Date : 2025-05-13
RETRACTION: Y. Nie, G. Yao, Y. Wei, S. Wu, W. Zhang, X. Xu, G. Li, F. Zhou, and Z. Yang, “,” Environmental Toxicology (EarlyView): https://doi.org/10.1002/tox.24243.The above article, published online on 4 April 2024 in Wiley Online Library (http://onlinelibrary.wiley.com/), has been retracted by agreement between the journal Editor‐in‐Chief, April Rodd; and Wiley Periodicals LLC. Following an investigation
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RETRACTION: Pachymic Acid Activates TP53INP2/TRAF6/Caspase‐8 Pathway to Promote Apoptosis in Renal Cell Carcinoma Cells Environ. Toxicol. (IF 4.4) Pub Date : 2025-05-13
RETRACTION: X. Li, A. He, C. Liu, Y. Li, Y. Luo, W. Xiong, W. Nian, and D. Zuo, “,” Environmental Toxicology (EarlyView): https://doi.org/10.1002/tox.24195.The above article, published online on 1 April 2024 in Wiley Online Library (http://onlinelibrary.wiley.com/), has been retracted by agreement between the journal Editor‐in‐Chief, April Rodd; and Wiley Periodicals LLC. Following an investigation
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RETRACTION: Deciphering the Prognostic Landscape of Osteosarcoma: Integrating the Roles of Hippo Pathway Genes, Programmed Cell Death, and the Tumor Immune Microenvironment Environ. Toxicol. (IF 4.4) Pub Date : 2025-05-10
RETRACTION: H. Ma, Y. Zhang, J. Li, T. Xie, and Z. Zhao, “,” Environmental Toxicology (EarlyView): https://doi.org/10.1002/tox.24280.The above article, published online on 15 April 2024 in Wiley Online Library (http://onlinelibrary.wiley.com/), has been retracted by agreement between the journal Editor‐in‐Chief, April Rodd; and Wiley Periodicals LLC. Following an investigation by the publisher, the
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RETRACTION: Protective Effect of Hibifolin on Lipopolysaccharide‐Induced Acute Lung Injury Through Akt Phosphorylation and NFκB Pathway Environ. Toxicol. (IF 4.4) Pub Date : 2025-05-10
RETRACTION: Y.‐Y. Ng, Y.‐C. Ho, C.‐H. Yen, S.‐S. Lee, C.‐C. Tseng, S.‐W. Wu and Y.‐H. Kuan, “,” Environmental Toxicology 40, no. (2025): 524–531, https://doi.org/10.1002/tox.24383.The above article, published online on 9 August 2024 in Wiley Online Library (http://onlinelibrary.wiley.com/), has been retracted by agreement between the authors; the journal Editor‐in‐Chief, April Rodd; and Wiley Periodicals
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RETRACTION: Single‐Cell Transcriptome Analysis Reveals Intratumoral Heterogeneity in Lung Adenocarcinoma Environ. Toxicol. (IF 4.4) Pub Date : 2025-05-10
RETRACTION: H. Xu, L. Jiang, L. Qin, P. Shi, P. Xu, and C. Liu, “,” Environmental Toxicology 39, no. (2024): 1847–1857, https://doi.org/10.1002/tox.24048.The above article, published online on 22 December 2023 in Wiley Online Library (http://onlinelibrary.wiley.com/), has been retracted by agreement between the journal Editor‐in‐Chief, April Rodd; and Wiley Periodicals LLC. Following an investigation
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RETRACTION: Prognostic Impact of Lactylation‐Associated Gene Modifications in Clear Cell Renal Cell Carcinoma: Insights into Molecular Landscape and Therapeutic Opportunities Environ. Toxicol. (IF 4.4) Pub Date : 2025-05-10
RETRACTION: J. Liu, P. Chen, J. Zhou, H. Li, and Z. Pan, “,” Environmental Toxicology 39, no. (2024): 1360–1373, https://doi.org/10.1002/tox.24040.The above article, published online on 16 November 2023 in Wiley Online Library (http://onlinelibrary.wiley.com/), has been retracted by agreement between the journal Editor‐in‐Chief, April Rodd; and Wiley Periodicals LLC. Following an investigation by the
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RETRACTION: Characterization of m6A RNA Methylation Mediated Immune Heterogeneity and Functional Validation in Hepatocellular Carcinoma Environ. Toxicol. (IF 4.4) Pub Date : 2025-05-10
RETRACTION: C. Zhang, Y. Huang, M. Liang, J. Wu, and G. Wang, “,” Environmental Toxicology (EarlyView): https://doi.org/10.1002/tox.24167.The above article, published online on 26 February 2024 in Wiley Online Library (http://onlinelibrary.wiley.com/), has been retracted by agreement between the journal Editor‐in‐Chief, April Rodd; and Wiley Periodicals LLC. Following an investigation by the publisher
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RETRACTION: Research on the Toxicological Prognostic Significance of Age‐Related Genes in Endometrial Cancer Unveiling Key Factors in Patient Prognosis Environ. Toxicol. (IF 4.4) Pub Date : 2025-05-10
RETRACTION: Y. Yin, Q. Niu, Z. Wei, Y. Wang, G. Li, W. Zhang, K. Guo, and X. Yao, “,” Environmental Toxicology (EarlyView): https://doi.org/10.1002/tox.24219.The above article, published online on 9 April 2024 in Wiley Online Library (http://onlinelibrary.wiley.com/), has been retracted by agreement between the journal Editor‐in‐Chief, April Rodd; and Wiley Periodicals LLC. Following an investigation
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RETRACTION: RSPO2‐Associated Mitochondrial Metabolism Defines Molecular Subtypes with Distinct Clinical and Immune Features in Esophageal Cancer Environ. Toxicol. (IF 4.4) Pub Date : 2025-05-10
RETRACTION: Q. Peng, T. Cao, X. Yang, Z. Ye, J. Wang, S. Chen, Y. Yu, Y. Yu, W. Xue, Z. Chen, and J. Fan, “,” Environmental Toxicology (EarlyView): https://doi.org/10.1002/tox.24209.The above article, published online on 16 March 2024 in Wiley Online Library (http://onlinelibrary.wiley.com/), has been retracted by agreement between the journal Editor‐in‐Chief, April Rodd; and Wiley Periodicals LLC
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RETRACTION: Prediction of Potential Targets and Toxicological Insights of Astragalus in Liver Cancer Based on Network Pharmacology: Integrating Systems Biology, Drug Interaction Networks, and Toxicological Perspectives Environ. Toxicol. (IF 4.4) Pub Date : 2025-05-10
RETRACTION: M. Zou, Z. Zheng, Z. Xiahou, and J. Cao, “,” Environmental Toxicology (EarlyView): https://doi.org/10.1002/tox.24189.The above article, published online on 13 March 2024 in Wiley Online Library (http://onlinelibrary.wiley.com/), has been retracted by agreement between the journal Editor‐in‐Chief, April Rodd; and Wiley Periodicals LLC. Following an investigation by the publisher, the parties
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Dendranthema oreastrum (Hance) Y.Ling Attenuates Oxidative Stress and Airway Inflammation in a Murine Model of Lipopolysaccharide‐Induced Acute Lung Injury Environ. Toxicol. (IF 4.4) Pub Date : 2025-04-23
Ji‐Hye Ha, Ba‐Wool Lee, Da‐Hye Yi, Seong‐Hun Jeong, Ju‐Hong Kim, Hyun‐Jae Jang, Ju Hwan Jeong, Ji‐Young Park, Hyung Jae Jeong, Hyung‐Jun Kwon, Young‐Bae Ryu, In‐Chul LeeWe examined the antioxidant and anti‐inflammatory effects of the methanolic extract of Dendranthema oreastrum (Hance) Y.Ling, commonly known as “Gu‐Jeol‐Cho” in Korea and widely found across East Asia, using an LPS‐induced acute lung injury (ALI) mouse model and TNF‐α‐stimulated NCI‐H292 cells. LPS was intratracheally administered at 20 μg/50 μL/mouse for 3 days. From test day 1 to 5, experimental
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RETRACTION: Scoparone Inhibits the Development of Hepatocellular Carcinoma by Modulating the p38 MAPK/Akt/NF‐κB Signaling in Nonalcoholic Fatty Liver Disease Mice Environ. Toxicol. (IF 4.4) Pub Date : 2025-04-22
RETRACTION: M. Ye, C. Liu, J. Liu, F. Lu, J. Xue, F. Li, and Y. Tang, “,” Environmental Toxicology 39, no. (2024): 551–561, https://doi.org/10.1002/tox.23851.The above article, published online on 12 July 2023, in Wiley Online Library (http://onlinelibrary.wiley.com/), has been retracted by agreement between the journal Editor‐in‐Chief, April Rodd; and Wiley Periodicals LLC. Following an investigation
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RETRACTION: Exosomal miRNA‐166‐5p Derived from G‐MDSCs Promotes Proliferation by Targeting ITM3E in Colorectal Cancer Environ. Toxicol. (IF 4.4) Pub Date : 2025-04-22
RETRACTION: T. Ma, J. Jiang, M. Shi, and H. Xu, “,” Environmental Toxicology 39, no. (2024): 803–814, https://doi.org/10.1002/tox.23980.The above article, published online on 4 October 2023, in Wiley Online Library (http://onlinelibrary.wiley.com/), and its correction, has been retracted by agreement between the journal Editor‐in‐Chief, April Rodd; and Wiley Periodicals LLC. Following an investigation
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RETRACTION: Value of Hepatic Artery Digital Subtraction Angiography in the Detection of Small Hepatocellular Carcinoma Lesions Environ. Toxicol. (IF 4.4) Pub Date : 2025-04-22
RETRACTION: T. Bai, S. Lu, J. Chen, J. Ye, X. Wang, Z. Tang, H. Fu, L. Li, and F. Wu, “,” Environmental Toxicology 39, no. (2024): 4754–4762, https://doi.org/10.1002/tox.24316.The above article, published online on 20 August 2024, in Wiley Online Library (http://onlinelibrary.wiley.com/), has been retracted by agreement between the journal Editor‐in‐Chief, April Rodd; and Wiley Periodicals LLC. Following
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RETRACTION: FOXA2 Suppresses Gallbladder Carcinoma Cell Migration, Invasion, and Epithelial‐Mesenchymal Transition by Targeting SERPINB5 Environ. Toxicol. (IF 4.4) Pub Date : 2025-04-22
RETRACTION: L. Hong, M. Chen, M. Huang, W. Chen, X. Abudukeremu, F. She, and Y. Chen, “,” Environmental Toxicology 39, no. (2024): 708–722, https://doi.org/10.1002/tox.23953.The above article, published online on 4 September 2023, in Wiley Online Library (http://onlinelibrary.wiley.com/), has been retracted by agreement between the journal Editor‐in‐Chief, April Rodd; and Wiley Periodicals LLC. Following
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RETRACTION: Elucidating the Molecular Mechanisms of Sepsis: Identifying Key Aging‐Related Biomarkers and Potential Therapeutic Targets in the Treatment of Sepsis Environ. Toxicol. (IF 4.4) Pub Date : 2025-04-22
RETRACTION: J. Zhou, J. Liu, C. Zhang, Y. Zhou, Z. Zheng, and H. Li, “,” Environmental Toxicology 39, no. (2024): 3341–3355, https://doi.org/10.1002/tox.24198.The above article, published online on 5 March 2024, in Wiley Online Library (http://onlinelibrary.wiley.com/), has been retracted by agreement between the journal Editor‐in‐Chief, April Rodd; and Wiley Periodicals LLC. Following an investigation
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RETRACTION: Eosinophils and Risk of Ulcerative Colitis in European Population: Evidence from Mendelian Randomization Study Environ. Toxicol. (IF 4.4) Pub Date : 2025-04-22
RETRACTION: Y. Shao, C. Liu, X. Wang, and W. Zhu, “,” Environmental Toxicology 39, no. (2024): 4669–4676, https://doi.org/10.1002/tox.24314.The above article, published online on 29 April 2024 in Wiley Online Library (http://onlinelibrary.wiley.com/), has been retracted by agreement between the journal Editor‐in‐Chief, April Rodd; and Wiley Periodicals LLC. Following an investigation by the publisher
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RETRACTION: Integrated Analysis of Gut Microbiota and Metabolomic Profiling in Colorectal Cancer Metastasis Environ. Toxicol. (IF 4.4) Pub Date : 2025-04-22
RETRACTION: Y. Xia, L. Duan, X.L. Zhang, Y.J. Niu, and X. Ling, “,” Environmental Toxicology 39, no. (2024): 4467–4478, https://doi.org/10.1002/tox.24228.The above article, published online on 14 March 2024 in Wiley Online Library (http://onlinelibrary.wiley.com/), has been retracted by agreement between the journal Editor‐in‐Chief, Christyn Bailey; and Wiley Periodicals LLC. Following an investigation
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Analysis of PM2.5 Morphology, Composition and Health Risk in a Multi‐Chair Dental Clinic Environ. Toxicol. (IF 4.4) Pub Date : 2025-04-09
Fengqin Tang, Shengcai Qi, Xiaoshan Tang, Xueyun Wen, Yiming Zhang, Guotao Peng, Jieying Huang, Guangwei Shang, Xu Zhang, Fubo Chen, Yuanzhi Xu, Jing CaiParticulate matter with aerodynamic diameter ≤ 2.5 μm (PM2.5) at high concentrations in dental clinics poses significant health risks to healthcare professionals. However, the morphology and chemical composition of PM2.5 in specific environments are not yet fully elucidated. In this study, we investigated the concentration, morphology, chemical composition, and health assessment of PM2.5 collected
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Induction of Cuproptosis by Dichloromethane Extract From Patrinia scabiosaefolia Fisch on K562 Cells Environ. Toxicol. (IF 4.4) Pub Date : 2025-04-04
Yuan Lu, Leyuan Mi, Peipei Zhang, Yang Chen, Xinyi Bai, Kejing Li, Ying Zhang, Juan LiCuproptosis is a newly identified form of cell death that relies on copper (Cu) ionophores to transport Cu into cancer cells. As a perennial herb, Patrinia scabiosaefolia Fisch (PS) has garnered significant attention owing to its analgesic, anti‐inflammatory, antibacterial, and antitumor properties. Previous research has shown that the extract from PS (DEPS) can inhibit the growth of leukemia cell
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Effects of Glyphosate on Zebrafish (Danio rerio) Developmental Toxicity Environ. Toxicol. (IF 4.4) Pub Date : 2025-04-04
Ning Zhou, Ruirui Li, Jin Lu, Jiagao Cheng, Wenping Xu, Liming Tao, Yang ZhangGlyphosate has been widely used in agricultural production as a highly effective, low‐toxic, broad‐spectrum organophosphorus herbicide. However, there has been controversy about whether it is toxic to the nervous system. In order to explore this issue in depth, the present study analyzed the molecular mechanism of action of glyphosate from four perspectives, namely, gene regulation, protein expression
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Environmentally Relevant Concentrations of Commercial Titanium Dioxide Nanoparticles Induce Ferroptosis in HUVECs Environ. Toxicol. (IF 4.4) Pub Date : 2025-04-04
Fangfang Huang, Yashi Feng, Zi‐An Wang, Yunchang Cao, Qiong Yan, Wuxiang Wang, Shaolong FengTitanium dioxide nanoparticles (TiO2‐NPs) have been ever increasingly exposed to people through all possible routes, while studies focusing on their potential cardiovascular risks are relatively lacking, especially the underlying biological mechanisms that are not yet elucidated. In this study, the ferroptotic effect of TiO2‐NPs (30 nm) at environmentally relevant concentrations (0, 3, 12, and 48 μg/mL)
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Chlorpyrifos Induces Apoptosis in Macrophages by Activating Both Intrinsic and Extrinsic Apoptotic Pathways Environ. Toxicol. (IF 4.4) Pub Date : 2025-03-19
Chen‐Yu Chiang, Shin‐Wu Liu, Chun‐Jung Chen, Wen‐Ying ChenAlthough chlorpyrifos poses considerable risks to the environment and human health, it is still used in many countries. This pesticide has various toxic effects on humans, including neurotoxicity, reproductive toxicity, genotoxicity, and organ damage caused by oxidative stress and DNA damage. However, its specific toxicity to the immune system remains unclear. In this study, we explored the intrinsic
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RETRACTION: An Innovative Predictive Model for Cervical Cancer Constructed Around a Gene Profile Associated With Cholesterol Metabolism Environ. Toxicol. (IF 4.4) Pub Date : 2025-03-12
RETRACTION: T. Pu, Y. Jin, C. Tang, J. Fu, C. Zhang, B. Su, and A. Cao, “,” Environmental Toxicology 39, no. (2024): 1055–1071, https://doi.org/10.1002/tox.23969.The above article, published online on 11 September 2023, in Wiley Online Library (http://onlinelibrary.wiley.com/), has been retracted by agreement between the journal Editor‐in‐Chief, Paul Tchounwou; and Wiley Periodicals LLC. Following
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RETRACTION: Comprehensive Analysis of m6A Modification Patterns and m6A‐Related lncRNAs as Potential Biomarkers in Lung Adenocarcinoma Environ. Toxicol. (IF 4.4) Pub Date : 2025-03-12
RETRACTION: S. Wang, X. Gu, D. Xu, B. Liu, K. Qin, and X. Yuan, “,” Environmental Toxicology 39, no. (2024): 2285–2303, https://doi.org/10.1002/tox.24110.The above article, published online on 26 December 2023, in Wiley Online Library (http://onlinelibrary.wiley.com/), has been retracted by agreement between the journal Editor‐in‐Chief, Christyn Bailey; and Wiley Periodicals LLC. Following an investigation
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RETRACTION: Pathogenomics Model for Personalized Medicine in Cervical Cancer: Cross‐Talk of Gene Expressions and Pathological Images Related to Oxidative Stress Environ. Toxicol. (IF 4.4) Pub Date : 2025-03-12
RETRACTION: J. Li, S. Chen, J. Wu, X. Liu, H. Liu, Y. Liu, and Z. Zhu, “,” Environmental Toxicology 39, no. (2024): 751–767, https://doi.org/10.1002/tox.23974.The above article, published online on 26 September 2023, in Wiley Online Library (http://onlinelibrary.wiley.com/), has been retracted by agreement between the journal Editor‐in‐Chief, Paul Tchounwou; and Wiley Periodicals LLC. Following an
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Unraveling the Causal Relationship Between 731 Immunocyte Phenotypes and Asthma Risk: A Bidirectional Mendelian Randomization Analysis Environ. Toxicol. (IF 4.4) Pub Date : 2025-03-11
Jie Lin, Zhan Zhang, Qiang Zhou, Jiayi Shi, Wanqing Li, Sen Lin, Hu Tang, Zheyu Zhang, Tianfeng Chen, Xiaojun Cai, Longhe CaoGrowing evidence suggests an association between various immune cell phenotypes and the development of asthma. However, it is still not entirely clear whether specific immune cell phenotypes might causally contribute to the risk of asthma. Despite further studies required to validate this claim, our study delves deeper into explaining this relationship and paving the way toward new therapeutic approaches
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Nanosized Ginger‐Derived Phenolic Zingerone Obstructs Cell Cycle G2/M Progression and Initiates Apoptosis in Human Colorectal Cancer Environ. Toxicol. (IF 4.4) Pub Date : 2025-03-11
Jui‐Ho Wang, Yun‐Wen Chen, Shuchen Hsieh, Mei‐Lang KungColorectal cancer (CRC) has become one of the most arduous challenges in contemporary cancer treatment. In nanomedicine, biomedical methodologies and nanomaterials are combined to develop novel and effective treatments for illnesses, infections, and cancer. The characteristics of nanotechnology are promising for addressing the urgent problems of modern cancer therapeutics, such as tumor recurrence
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RETRACTION: Transcriptional Factor BRD4 Promotes the Stemness of Esophageal Cancer by Activating the Nuclear PD‐L1/RelB Axis Environ. Toxicol. (IF 4.4) Pub Date : 2025-03-11
RETRACTION: S. Li, Q. Guo, R. Guo, and H. Xu, “,” Environmental Toxicology 39, no. (2024): 669–679, https://doi.org/10.1002/tox.23939.The above article, published online on 24 August 2023, in Wiley Online Library (http://onlinelibrary.wiley.com/), has been retracted by agreement between the journal Editor‐in‐Chief, Paul Tchounwou; and Wiley Periodicals LLC. Following an investigation by the publisher
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RETRACTION: SIK2‐Positive Tumor Epithelial Cells in Breast Cancer Maybe Potential Anti‐Cancer Messengers: A Systematic Analysis from a Single‐Cell Perspective Environ. Toxicol. (IF 4.4) Pub Date : 2025-03-11
RETRACTION: Q. Wu, C. Qu, L. Xin, F. Yang, and L. Xu, “,” Environmental Toxicology 39, no. (2024): 768–782, https://doi.org/10.1002/tox.23987.The above article, published online on 29 September 2023, in Wiley Online Library (http://onlinelibrary.wiley.com/), has been retracted by agreement between the journal Editor‐in‐Chief, Paul Tchounwou; and Wiley Periodicals LLC. Following an investigation by
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Distinct Disruptive Effects of Methylparaben and Propylparaben on the Prostate and Gonads of Adult Gerbils Environ. Toxicol. (IF 4.4) Pub Date : 2025-03-11
Edvaldo Mendes Silva, Janaína Ribeiro Costa, Ariany Angéllica Caballero Corrêa, Naiara Cristina de Souza Ribeiro, Hericles Mesquita Campos, Elizabeth Pereira Mendes, Mara Rubia Marques, Sebastião Roberto Taboga, Paulo César Ghedini, Sérgio Alexandre Alcantara dos Santos, Manoel Francisco Biancardi, Fernanda Cristina Alcantara dos SantosParabens are chemicals used as preservatives in food, personal care products, and pharmaceuticals. Detectable paraben levels are found in water, air, and soil, making human and animal exposure unavoidable. This study evaluated the effects of methylparaben, propylparaben, and their mixture on the prostate and gonads of male and female gerbils. Gerbils aged 90 days were assigned to the groups: (M) 10
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Chronic Exposure to an Environmentally Relevant Mixture of Endocrine Disruptors Alters Nuclear Phenotype and Induces Renal Fibrosis in Rats Environ. Toxicol. (IF 4.4) Pub Date : 2025-03-11
Karianne Delalibera Hinokuma, Maria Luiza Silva Ricardo, Andreia Yuri Yoshigae, Thaina Cavalleri Sousa, Letícia Pereira de Souza, Gisele Alborghetti Nai, Glaura Scantamburlo Alves Fernandes, Ivana Regina da Costa, Thiago Rentz Ferreira Laginski, Leonardo de Oliveira MendesThe exposome is considered an assessment of environmental exposure and associated biological responses over an individual's lifetime. Endocrine disruptors chemicals (EDCs), an important component of such exposures, exert adverse effects on human health. The kidneys are targets for EDCs because of their characteristic of bioaccumulation. Therefore, we aimed to evaluate cellular and tissue changes in
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Irigenin Alleviates Blue Light‐Induced Retinal Damage by Upregulating Antioxidative Defense System via Nrf2 Pathway In Vivo and In Vitro Environ. Toxicol. (IF 4.4) Pub Date : 2025-03-11
Kun‐Lin Yeh, Yu‐Hsiang Kuan, Sheng‐Wen Wu, Chen‐Yu Chiang, Chun‐Jung Chen, Wen‐Ying Chen, Chi‐Chung ChouThis research aimed to assess the potential of irigenin to attenuate blue light (BL)‐induced apoptosis in human adult retinal pigment epithelial (hARPE‐19) cells loaded with N‐retinylidene‐N‐retinylethanolamine (A2E, DA50062). Furthermore, the study investigated the associated molecular mechanisms. Cell viability was assessed using the MTT assay, and flow cytometry was employed to evaluate reactive
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N‐Acetyl‐L‐Cysteine Mediated Attenuation of Cadmium Induced Oxidative Stress and Apoptosis in Ovarian Antral Follicles In Vitro Environ. Toxicol. (IF 4.4) Pub Date : 2025-03-10
Prerna Bikal, Jitender Kumar BhardwajFemale fertility has been demonstrated to be directly correlated with cadmium, a heavy metal contaminant that is widely present in the environment. N‐acetyl cysteine (NAC), a powerful antioxidant, has been shown to have therapeutic effects for a number of ailments. NAC's potential to prevent ovarian toxicity caused by Cd is still unknown. Therefore, the objective of the current study was to evaluate
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Modulatory Effects of Ophiocordyceps sinensis Mycelia on Hepatosteatosis Development in a High‐Fat Dietary Habit Environ. Toxicol. (IF 4.4) Pub Date : 2025-02-21
Yi‐Ling Lin, Christoper Caesar Yudho Sutopo, Yi‐Feng Kao, Jung‐Kai Tseng, Yi‐Chen ChenThe global rise in obesity is closely associated with the increasing prevalence of nonalcoholic fatty liver disease (NAFLD) and metabolic syndromes, posing significant health challenges. This study explored the ameliorative effects of Ophiocordyceps sinensis mycelia (TCM‐NA01 formula: 1.4 mg adenosine and 55.2 mg polysaccharide/capsule) on hepatosteatosis development in a high‐fat diet (HFD)‐fed mice
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Exposure to Polystyrene Microplastic Differentially Affects the Colon and Liver in Adult Male Mice Environ. Toxicol. (IF 4.4) Pub Date : 2025-02-19
Somaye Zangene, Hassan Morovvati, Hojat Anbara, Nicola BernabòMicroplastics (MPs) have emerged as novel environmental pollutant. Their ubiquity in natural environments and the global dissemination of plastic particles through food and drink have led to the oral ingestion of these particles by all kinds of living organism. In this investigation, male mice were subjected to exposure to 2 μm virgin PS‐MPs for 6 weeks. To accomplish this, 36 adult male NMRI mice
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Maternal Exposure of SD Rats to Benzo[a]Pyrene Impairs Neurobehavior and Hippocampal Synaptic Ultrastructure in Offspring via Downregulating Synaptic‐Associated Factors Environ. Toxicol. (IF 4.4) Pub Date : 2025-02-19
Yu Zhang, Yuting Guo, Linhu Du, Junxiu Zhao, Xiaorui Ci, Jinzhu Yin, Qiao Niu, Yiqun Mo, Qunwei Zhang, Jisheng NieBenzo[a]pyrene (B[a]P) is a carcinogenic contaminant widely present in the environment. Recently, increasing studies have paid attention to the developmental neurotoxicity of B[a]P in offspring in their early life stages; however, the underlying molecular mechanisms have not been clearly elucidated. In this study, we aimed to evaluate the effects of prenatal B[a]P exposure on neurobehavior of pups
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RETRACTION: Zinc Finger Protein207 Orchestrates Glioma Migration Through Regulation of Epithelial‐Mesenchymal Transition Environ. Toxicol. (IF 4.4) Pub Date : 2025-02-17
RETRACTION: C. Zhao, Y. Guo, Y. Chen, G. Shang, D. Song, J. Wang, J. Yang, and H. Zhang, “Zinc Finger Protein207 Orchestrates Glioma Migration Through Regulation of Epithelial‐Mesenchymal Transition,” Environmental Toxicology 40, no. 5 (2025): E29–E43: https://doi.org/10.1002/tox.24271.The above article, published online on 9 April 2024, in Wiley Online Library (http://onlinelibrary.wiley.com/), has
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Effects of D‐Tetramethrin on Zebrafish Development and Immune System Environ. Toxicol. (IF 4.4) Pub Date : 2025-02-17
Yang Li, Keyuan Zhong, Sijie Zhang, Shiyi Duan, Kaijie Huang, Xiaofang Che, Xinchun Guo, Huiqiang LuD‐tetramethrin is a common insecticide that is important for the control of mosquito‐transmitted diseases such as malaria and dengue and, due to its widespread use, it is frequently detected in environmental systems. However, there is currently very little information on the influence of D‐tetramethrin on non‐target organisms. In this study, zebrafish embryos were exposed to various concentrations
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RETRACTION: MiR‐375 Impairs Breast Cancer Cell Stemness by Targeting the KLF5/G6PD Signaling Axis Environ. Toxicol. (IF 4.4) Pub Date : 2025-02-17
RETRACTON: H. Chen, S. Hou, H. Zhang, B. Zhou, H. Xi, X. Li, Z. Lufeng, and Q. Guo, “MiR‐375 Impairs Breast Cancer Cell Stemness by Targeting the KLF5/G6PD Signaling Axis,” Environmental Toxicology 40, no. 5 (2025): E1–E13: https://doi.org/10.1002/tox.24204.The above article, published online on 12 March 2024, in Wiley Online Library (http://onlinelibrary.wiley.com/), has been retracted by agreement
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RETRACTION: Development of Gene Panel for Predicting Recurrence in Early‐Stage Cervical Cancer Patients Environ. Toxicol. (IF 4.4) Pub Date : 2025-02-17
RETRACTION: Y. Ma and W. Zhu, “Development of Gene Panel for Predicting Recurrence in Early‐Stage Cervical Cancer Patients,” Environmental Toxicology 40, no. 5 (2025): E14–E28: https://doi.org/10.1002/tox.24270.The above article, published online on 2 April 2024, in Wiley Online Library (http://onlinelibrary.wiley.com/), has been retracted by agreement between the journal Editor‐in‐Chief, Christyn
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RETRACTION: Erianin Suppressed Lung Cancer Stemness and Chemotherapeutic Sensitivity via Triggering Ferroptosis Environ. Toxicol. (IF 4.4) Pub Date : 2025-02-17
RETRACTION: J. Lv, Z. Wang, and H. Liu, “Erianin Suppressed Lung Cancer Stemness and Chemotherapeutic Sensitivity via Triggering Ferroptosis,” Environmental Toxicology 39, no. 2 (2024): 479‐486, https://doi.org/10.1002/tox.23832.The above article, published online on 20 May 2023, in Wiley Online Library (http://onlinelibrary.wiley.com/), has been retracted by agreement between the journal Editor‐in‐Chief
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RETRACTION: NIK‐Mediated Reactivation of SIX2 Enhanced the CSC‐like Traits of Hepatocellular Carcinoma Cells Through Suppressing Ubiquitin–Proteasome System Environ. Toxicol. (IF 4.4) Pub Date : 2025-02-17
RETRACTION: L. Daren, Y. Dan, W. Jinhong, and L. Chao, “NIK‐Mediated Reactivation of SIX2 Enhanced the CSC‐like Traits of Hepatocellular Carcinoma Cells Through Suppressing Ubiquitin–Proteasome System,” Environmental Toxicology 39, no. 2 (2024): 583‐591, https://doi.org/10.1002/tox.23892.The above article, published online on 17 July 2023, in Wiley Online Library (http://onlinelibrary.wiley.com/),
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RETRACTION: USP14 Promotes the Proliferation of Cervical Cancer via Upregulating β‐Catenin Environ. Toxicol. (IF 4.4) Pub Date : 2025-02-17
RETRACTION: H. Song, J. Qiu, and K. Hua, “USP14 Promotes the Proliferation of Cervical Cancer via Upregulating β‐Catenin,” Environmental Toxicology 39, no. 2 (2024): 1031‐1043, https://doi.org/10.1002/tox.23990.The above article, published online on 9 December 2023, in Wiley Online Library (http://onlinelibrary.wiley.com/), has been retracted by agreement between the journal Editor‐in‐Chief, Christyn
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RETRACTION: CAB39 Modulates Epithelial–Mesenchymal Transition Through NF‐κB Signaling Activation, Enhancing Invasion, and Metastasis in Bladder Cancer Environ. Toxicol. (IF 4.4) Pub Date : 2025-02-17
RETRACTION: J. Huang, H. Deng, S. Xiao, Y. Lin, Z. Yu, X. Xu, L. Peng, H. Chao, and T. Zeng, “CAB39 Modulates Epithelial–Mesenchymal Transition Through NF‐κB Signaling Activation, Enhancing Invasion, and Metastasis in Bladder Cancer,” Environmental Toxicology 39, no. 10 (2024): 4791‐4802, https://doi.org/10.1002/tox.24333.The above article, published online on 22 August 2024, in Wiley Online Library