BACKGROUND Osgood-Schlatter has, until recently, been suggested to be a benign condition, affecting adolescents in terms of knee pain and decreased sports participation during growth, with no long-term consequences seen later in adulthood. OBJECTIVES The objectives of this study were to describe the long-term knee health in adults with a history of Osgood-Schlatter, compare these findings with healthy population estimates, and investigate if explanatory variables are associated with current knee health. METHODS The Danish Patient Registry identified patients ≥ 18 years diagnosed with adolescent Osgood-Schlatter in hospitals during 1977-2020. All cases participated in a survey about knee-related health and comorbidities. Existing literature was sourced for the healthy population estimates for comparisons. Explanatory variables were recalled Osgood-Schlatter duration, pain levels, restrictions, and current tibial tubercle prominence. RESULTS Of 1281 identified patients, 400 responded. Most reported having a current bony prominence of the tibial tubercle (85%) and sustained pain/problems from the same area (73%). Compared with healthy population estimates, Osgood-Schlatter cases scored lower on the Knee Injury and Osteoarthritis Outcome Score on all subscales (p < 0.05), particularly for "sport/rec" and "quality of life" (Cohen's d > 0.8). Similarly, cases exhibited a large risk of "jumper's knee" (odds ratio: 70.4 [95% confidence intervals, CI: 32.9; 155.0], p < 0.0001). Symptom duration and pain levels were negatively associated with several outcomes (p < 0.05). CONCLUSIONS Adults with a history of Osgood-Schlatter have significantly worse long-term knee health than what is observed from healthy population estimates. Recalled longer symptom duration and higher pain levels were associated with worse current knee health. This information should potentially guide management to maintain knee health over time, as the condition is not always as benign and self-limiting as previously thought. REGISTRATION NCT04313621.

中文翻译：

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有青少年 Osgood-Schlatter 病史的成人的长期膝关节健康：1977-2020 年丹麦二级保健患者的全国队列研究。

背景直到最近，Osgood-Schlatter 才被认为是一种良性疾病，影响青少年的膝关节疼痛和成长过程中运动参与度降低，在成年后期没有看到长期后果。目的 本研究的目的是描述有 Osgood-Schlatter 病史的成年人的长期膝关节健康，将这些发现与健康人群估计进行比较，并调查解释变量是否与当前的膝关节健康相关。方法 丹麦患者登记处确定了 1977-2020 年期间在医院诊断患有青少年 Osgood-Schlatter 的 18 ≥患者。所有病例都参加了关于膝关节相关健康和合并症的调查。现有文献来源于健康种群估计值以进行比较。解释变量回忆 Osgood-Schlatter 持续时间、疼痛程度、限制和当前胫骨结节突出。结果 在 1281 名已确定的患者中，400 名做出了回应。大多数报告说目前胫骨结节骨突出 （85%） 和同一区域的持续疼痛/问题 （73%）。与健康的人群估计相比，Osgood-Schlatter 病例在所有分量表上的膝关节损伤和骨关节炎结果评分得分较低 （p < 0.05），特别是在“运动/娱乐”和“生活质量”方面 （Cohen's d > 0.8）。同样，病例表现出 “跳线膝” 的较大风险 （比值比： 70.4 [95% 置信区间，CI： 32.9;155.0]，p < 0.0001）。症状持续时间和疼痛程度与几个结局呈负相关 （p < 0.05）。结论 有 Osgood-Schlatter 病史的成年人的长期膝关节健康状况明显差于从健康人群估计中观察到的膝关节健康状况。 回忆较长的症状持续时间和较高的疼痛程度与较差的当前膝关节健康状况有关。这些信息可能会指导管理层随着时间的推移保持膝关节健康，因为这种情况并不总是像以前认为的那样良性和自限性。注册 NCT04313621。